The NHS has launched the world’s largest trial of a potentially gamechanging blood test that aims to detect more than 50 types of cancer before symptoms appear.
More than 100,000 volunteers are being sought to provide blood samples at mobile test clinics in regions across England from Monday to assess how well the test works in the health service.
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More treatments are available for Covid-19 as hospitalizations spike, but some drugs are sitting on the shelves unused.
As record daily Covid-19 hospitalizations and deaths this month in the US have pushed the pandemic to new crisis levels, senior government health officials have lamented that many patients are not getting the drugs — including monoclonal antibodies, antivirals, and corticosteroids — available to treat the disease, leaving many doses unused.
“Even with a vaccine, we know we will not prevent every infection,” said US Surgeon General Jerome Adams on January 14 during a press conference. “So today we want to remind everyone that for those of you who do contract Covid, we have excellent treatments to keep you out of the hospital, to keep you out of the ICU, to help you recover quickly.”
Scientists will soon have the tools to rewrite the book of life, and in doing so, edit out sections that cause disease, piece by piece. But is the technology safe and will all of us get the benefits, or will it be the preserve of those who can afford it?
“Identification of these compounds means that we are one step closer to being able to molecularly diagnose dementia,” said senior author of the study, Professor Mitsuhiro Yanagida, who leads the G0 Cell Unit at OIST.
Summary: Researchers identified 33 metabolic compounds in blood samples that differed between those with dementia and cognitively healthy older adults. 7 of the metabolites were elevated in dementia patients, while 26 were at lower levels compared to samples of those without dementia. Elevating levels of those metabolites could have a neuroprotective effect against dementia.
Source: OIST
Continue reading “Signs of Dementia Are Written in the Blood” »
“We think that this indicates that gut bacteria and fungi influence anti-tumor immune responses in many, if not all, types of cancer.”
Cedars-Sinai Cancer researchers have discovered that intestinal microorganisms help regulate anti-tumor immune responses to radiation treatments, and that fungi and bacteria have opposing effects on those responses. The study, conducted in laboratory mice 0 illuminates a path toward improving the effectiveness of radiation and immune-based treatments for patients with melanoma, breast and many other cancers.
The study, published on Aug. 13 in the peer-reviewed journal Cancer Cell, builds on prior studies that focused on the role of intestinal bacteria in influencing immune responses to chemotherapy and immunotherapy. Here the investigators sought to determine what role both bacteria and fungi in the gut might play in the response to radiation therapy.
Continue reading “Radiation Therapy Effectiveness Influenced by Gut Fungi” »
Hwang and colleagues lay out their platform, which could one day be integrated not only into dental implants but other technologies, such as joint replacements, as well.
More than 3 million people in America have dental implants, used to replace a tooth lost to decay, gum disease, or injury. Implants represent a leap of progress over dentures or bridges, fitting much more securely and designed to last 20 years or more.
But often implants fall short of that expectation, instead needing replacement in five to 10 years due to local inflammation or gum disease, necessitating a repeat of a costly and invasive procedure for patients.
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Continue reading “FutureMan: The Future of Health and Fitness 2021-2150” »
Info for those who may need it.
The Editors of BMC Cancer and BMC Medicine invite of submissions to our ‘Targeted Therapy’ cross journal collection. Guest edited by Prof. Min Li (University of Oklahoma Health Sciences Center, USA) and Dr. Yanis Boumber (The Northwestern University, USA).
We advise to submit by 1st August 2021 if you would like your manuscript to be ready for the launch date.
A new Yale study provides important insights into breakthrough COVID-19 cases — instances where fully vaccinated individuals are infected by SARS-CoV-2 — and who is particularly vulnerable to serious illness.
In a study of hospitalized patients in the Yale New Haven Health System, researchers identified 969 individuals who tested positive for the SARS-CoV-2 infection during a 14-week period between March and July 2021. Of that group, 54 were fully vaccinated.
“These cases are extremely rare, but they are becoming more frequent as variants emerge and more time passes since patients are vaccinated,” said Hyung Chun, associate professor of medicine (cardiology) at Yale and senior author of the study published Sept. 7 in Lancet Infectious Diseases.
